Pauline Lukey: search on Z-Library

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1

Independent consultancy in drug discovery and development: a personal perspective

Lukey, Pauline T

Journal:

Future Drug Discovery

Year:

2019

Language:

english

File:

PDF, 476 KB

english, 2019

2

Basic fibroblast growth factor modulates the expression of glycophorin A and c-kit and inhibits erythroid differentiation in K562 cells

Patricia E. Burger, Pauline T. Lukey, Sandra Coetzee, E. Lynette Wilson

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 315 KB

english, 2002

3

Clofazimine-mediated regulation of human polymorphonuclear leukocyte migration by pro-oxidative inactivation of both leukoattractants and cellular migratory responsiveness

Ronald Anderson, Pauline Lukey, Constance Van Rensburg, Ursula Dippenaar

Journal:

International Journal of Immunopharmacology

Year:

1986

Language:

english

File:

PDF, 1.24 MB

english, 1986

4

Distribution of IFN-γ, IL-4 and TNF-α protein and CD8 T cells producing IL-12p40 mRNA in human lung tuberculous granulomas

Gael Fenhalls, Liesel Stevens, Juanita Bezuidenhout, Gillian E. Amphlett, Ken Duncan, Philip Bardin, Pauline T. Lukey

Journal:

Year:

2002

Language:

english

File:

PDF, 598 KB

english, 2002

5

Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling

Joanna C. Betts, Pauline T. Lukey, Linda C. Robb, Ruth A. McAdam, Ken Duncan

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 375 KB

english, 2002

6

Ascorbate and cysteine-mediated selective neutralisation of extracellular oxidants during N-formyl peptide activation of human phagocytes

Ronald Anderson, Pauline T. Lukey, Annette J. Theron, Ursula Dippenaar

Journal:

Inflammation Research

Year:

1987

Language:

english

File:

PDF, 851 KB

english, 1987

7

18F-Fluorodeoxyglucose positron emission tomography pulmonary imaging in idiopathic pulmonary fibrosis is reproducible: implications for future clinical trials

Thida Win, Tryphon Lambrou, Brian F. Hutton, Irfan Kayani, Nicholas J. Screaton, Joanna C. Porter, Toby M. Maher, Raymondo Endozo, Robert I. Shortman, Pauline Lukey, Ashley M. Groves

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2012

Language:

english

File:

PDF, 282 KB

english, 2012

8

Changes in the kinetics of intracellular IFN-γ production in TB patients during treatment

Hanne Veenstra, Ilse Crous, Shweta Brahmbhatt, Pauline Lukey, Nulda Beyers, Paul D. van Helden, Gerhard Walzl

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 611 KB

english, 2007

9

High levels of intracellular IL-4 are expressed in circulating apoptotic T cells in patients with tuberculosis and in community controls

Hanne Veenstra, Ralf Baumann, Pauline T. Lukey, Nulda Beyers, Paul D. van Helden, Gerhard Walzl

Journal:

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008

10

Benoxaprofen activates membrane-associated oxidative metabolism in human polymorphonuclear leucocytes by apparent modulation of protein kinase C

Pauline T. Lukey, Ronald Anderson, Ursula H. Dippenaar

Journal:

British Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 907 KB

english, 1988

11

Serodiagnostic markers for the prediction of the outcome of intensive phase tuberculosis therapy

Baumann, Ralf, Kaempfer, Susanne, Chegou, Novel N., Nene, Nonhlanhla F., Veenstra, Hanne, Spallek, Ralf, Bolliger, Chris T., Lukey, Pauline T., van Helden, Paul D., Singh, Mahavir, Walzl, Gerhard

Journal:

Year:

2013

Language:

english

File:

PDF, 199 KB

english, 2013

12

Population Pharmacokinetics of Losmapimod in Healthy Subjects and Patients with Rheumatoid Arthritis and Chronic Obstructive Pulmonary Diseases

Yang, Shuying, Lukey, Pauline, Beerahee, Misba, Hoke, Frank

Journal:

Clinical Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

13

Areas of normal pulmonary parenchyma on HRCT exhibit increased FDG PET signal in IPF patients

Win, Thida, Thomas, Benjamin A., Lambrou, Tryphon, Hutton, Brian F., Screaton, Nicholas J., Porter, Joanna C., Maher, Toby M., Endozo, Raymondo, Shortman, Robert I., Afaq, Asim, Lukey, Pauline, Ell, P

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2014

Language:

english

File:

PDF, 205 KB

english, 2014

14

Strategies for biomarker discovery in fibrotic disease

Marshall, Richard P., Simpson, Juliet K., Lukey, Pauline T.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 515 KB

english, 2013

15

HLA‐B*35–Restricted CD8 T Cell Epitopes in the Antigen 85 Complex of Mycobacterium tuberculosis

Klein, Michèl R., Smith, Steven M., Hammond, Abdulrahman S., Ogg, Graham S., King, Abigail S., Vekemans, Johan, Jaye, Assan, Lukey, Pauline T., McAdam, Keith P. W. J.

Journal:

The Journal of Infectious Diseases

Year:

2001

Language:

english

File:

PDF, 152 KB

english, 2001

16

Protein Expression in Mycobacterium tuberculosis Differs with Growth Stage and Strain Type

Pheiffer, Carmen, Betts, Joanna, Lukey, Pauline, Helden, Paul van

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

17

Gene‐Expression Patterns in Whole Blood Identify Subjects at Risk for Recurrent Tuberculosis

Mistry, Rohit, Cliff, Jacqueline M., Clayton, Christopher L., Beyers, Nulda, Mohamed, Yasmin S., Wilson, Paul A., Dockrell, Hazel M., Wallace, Don M., Helden, Paul D. van, Duncan, Ken, Lukey, Pauline

Journal:

The Journal of Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 3.53 MB

english, 2007

18

Evidence for In Vivo Generation of Cytotoxic T Cells: PPD-stimulated Lymphocytes from Tuberculous Pleural Effusions Demonstrate Enhanced Cytotoxicity with Accelerated Kinetics of Induction

Lorgat, Faizel, Keraan, Mustapha M., Lukey, Pauline T., Ress, Stanley R.

Journal:

American Review of Respiratory Disease

Year:

1992

Language:

english

File:

PDF, 583 KB

english, 1992

19

Associations between Toll-Like Receptors and Interleukin-4 in the Lungs of Patients with Tuberculosis

Fenhalls, Gael, Squires, Ginette R., Stevens-Muller, Liesel, Bezuidenhout, Juanita, Amphlett, Gillian, Duncan, Ken, Lukey, Pauline T.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 522 KB

english, 2003

20

Daily Home Spirometry: An Effective Tool for Detecting Progression in Idiopathic Pulmonary Fibrosis

Russell, Anne-Marie, Adamali, Huzaifa, Molyneaux, Philip L, Lukey, Pauline T, Marshall, Richard P., Renzoni, Elisabetta A, Wells, Athol U, Maher, Toby M

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

21

A First Time in Human, Microdose, Positron Emission Tomography Study of the Safety, Immunogenicity, Biodistribution and Radiation Dosimetry of [ 18 F]FB-A20FMDV2 for Imaging the Integrin αvβ6

Keat, Nicholas, Kenny, Julia, Chen, Keguan, Onega, Mayca, Garman, Nadia, Slack, Robert J, Parker, Christine A, Lumbers, Tom, Hallett, Will, Saleem, Azeem, Passchier, Jan, Lukey, Pauline T

Journal:

Journal of Nuclear Medicine Technology

Year:

2018

Language:

english

File:

PDF, 890 KB

english, 2018

22

Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants

Maden, Charlotte H., Fairman, David, Chalker, Michelle, Costa, Maria J., Fahy, William A., Garman, Nadia, Lukey, Pauline T., Mant, Tim, Parry, Simon, Simpson, Juliet K., Slack, Robert J., Kendrick, St

Journal:

European Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 575 KB

english, 2018

23

The topical study of inhaled drug (salbutamol) delivery in idiopathic pulmonary fibrosis

Usmani, Omar S., Biddiscombe, Martyn F., Yang, Shuying, Meah, Sally, Oballa, Eunice, Simpson, Juliet K., Fahy, William A., Marshall, Richard P., Lukey, Pauline T., Maher, Toby M.

Journal:

Respiratory Research

Year:

2018

Language:

english

File:

PDF, 1.83 MB

english, 2018

24

A Randomised, Placebo-Controlled Study of Omipalisib (PI3K/mTOR) in Idiopathic Pulmonary Fibrosis

Lukey, Pauline T., Harrison, Stephen A., Yang, Shuying, Man, Yim, Holman, Beverley F., Rashidnasab, Alaleh, Azzopardi, Gabrielle, Grayer, Michael, Simpson, Juliet K., Bareille, Philippe, Paul, Lyn, Wo

Journal:

European Respiratory Journal

Year:

2019

Language:

english

File:

PDF, 1.27 MB

english, 2019

25

Patient reported distress can aid clinical decision making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort

Stewart, Iain, McKeever, Tricia, Braybrooke, Rebecca, Oballa, Eunice, Simpson, Juliet K., Maher, Toby M., Marshall, Richard P., Lukey, Pauline T., Fahy, William A., Jenkins, Gisli, Saini, Gauri

Journal:

European Respiratory Journal

Year:

2019

File:

PDF, 4.14 MB

2019

26

HR‐pQCT Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta‐analysis

Mikolajewicz, Nicholas, Bishop, Nick, Burghardt, Andrew J, Folkestad, Lars, Hall, Anthony, Kozloff, Kenneth M, Lukey, Pauline T, Molloy‐Bland, Michael, Morin, Suzanne N, Offiah, Amaka C, Shapiro, Jay,

Journal:

Journal of Bone and Mineral Research

Year:

2019

File:

PDF, 4.49 MB

2019

27

Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)

Lukey, Pauline T., Coello, Christopher, Gunn, Roger, Parker, Christine, Wilson, Frederick J., Saleem, Azeem, Garman, Nadia, Costa, Maria, Kendrick, Stuart, Onega, Mayca, Kang’ombe, Arthur R., Listanco

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2019

File:

PDF, 3.07 MB

2019

28

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] C55. INTERSTITIAL LUNG DISEASE: DIAGNOSTIC AND THERAPEUTIC CONSIDERATIONS - Daily Hand-Held Spirometry For The Monitoring Of Patients With Idiopathic Pulmonary Fibrosis

Russell, Anne-Marie, Molyneaux, Philip L., Lukey, Pauline T., Fraser, Una H., Renzoni, Elizabeth A., Wells, Athol, Maher, Toby M.

Year:

2012

File:

PDF, 18 KB

2012

29

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] C41. OUTCOMES IN INTERSTITIAL LUNG DISEASE - Symptom Related Quality Of Life Measures In Patients With Idiopathic Pulmonary Fibrosis

Russell, Anne-Marie, Molyneaux, Philip L., Adamali, Huzaifa I., Fraser, Una H., Lukey, Pauline T., Wells, Athol, Maher, Toby

Year:

2012

File:

PDF, 24 KB

2012

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